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It has to be removed from the brain extracellular fluid through EAATs transporters (the most powerful of the active transporters) present in astrocytes (EAAT1-3), neurons (EAAT3) and at the abluminal side of the BBB (EAAT1-3) and through systems Xc and X G in the luminal membrane

Allergies typically involve excessive Th2 responses against external proteins, while autoimmune diseases involve Th1 or Th17 attacks on self-tissues

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