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The best non-diabetic body-composition anchor favors tirzepatide, about 75:25 fat-to-lean loss in its DXA data versus about 62:38 in semaglutides. This is cross-trial evidence, not a head-to-head maintenance-dose DXA result

This can indirectly support weight loss by helping to ease symptoms that make your best exercise and nutrition attempts more challenging

Common side effects: Gastrointestinal (nausea, diarrhea, vomiting, constipation) typically mildtomoderate and dosedependent

It lasts longer in the body, so patients need it less often

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