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Many cytokines use the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway to exert their effect in the pathology of RA, rendering them amenable to therapeutic blockade with Jakinibs which have proven effective for the treatment of RA

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Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells

Figure 4 7.2 Psoriasis Psoriasis is a chronic, non-infectious, systemic inflammatory disease of autoimmune origin

Differences between two and multiple populations were assessed using the two-tailed Students t- test and one-way ANOVA with Tukeys post-hoc test respectively

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