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Undoubtedly, drug-induced nephrotoxicity is a major cause of renal impairments and a potential impediment to the research and development of drugs, requiring more reliable and early diagnosis to avoid potentially fatal chronic conditions

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Joint discomfort is not listed as a recognised adverse effect in the BNF or licensed B12 product information, and most people taking B12 experience no musculoskeletal symptoms

J Nanobiotechnology (2024) 22(1):707

(That said, not all GLP-1 products on the market are FDA-approved

Journal of Pharmaceutics (2016) 12