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In people with obesity or metabolic dysfunction, amylin signaling is often blunted meaning the bodys natural braking system for eating isnt working properly

Others maintain continuous use

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However, high doses of vitamin B12, such as those used to treat a deficiency, might cause: Headache Nausea and vomiting Diarrhea Fatigue or weakness Its important to note that these side effects are generally mild and temporary

This interaction accelerates the damage caused by Syn PFFs to both ECs and neurons [225, 226]

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