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Children who are sick and fasting and are administered vaccines with prophylactic acetaminophen are much more likely to suffer acetaminophen toxicity

However, much of this is relative because Vitamin B12 is water soluble so a lot of it is wasted and passed by the body

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Experimental Eye Research , 137 , 5056

doi: 10.1016/j.lfs.2022.121072

BILAG, 2004 Development and initial validation of an updated version of the British Isles Lupus Assessment Groups disease activity index for patients with systemic lupus erythematosus