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31 (3), 564-579.e7

Retrieved October 31, 2015

J., Podell, E

Furthermore, GHK-Cu may reduce the number of Th17 cells

Tirzepatide Evidence level : FDA approved, strong clinical evidence SURMOUNT trials : SURMOUNT-1 (Jastreboff et al., 2022): 2,539 participants 72 weeks treatment Result: 20.9% average weight loss (highest dose) Superior to semaglutide Dual GLP-1/GIP mechanism SURMOUNT-2 (with diabetes): 14.7% weight loss Excellent HbA1c control Mechanism : Activates both GLP-1 and GIP receptors for enhanced effect