In biochemical research, GHK-Cu is notable because its endogenous concentration has been observed to decline significantly with age, correlating with a diminished capacity for tissue regeneration
PubMed 22962027 TB-4 Phase 1 human safety first-in-human randomized, double-blind, single- and multiple-dose Phase 1 of recombinant human thymosin 4 in healthy volunteers, no serious adverse events: PubMed 34346165
Neelakantan and colleagues (Biochem Pharmacol, 2017) then took the pharmacological step, reporting that selective, membrane-permeable small-molecule NNMT inhibitors reversed high-fat-diet-induced obesity in mice this is the study most directly relevant to the 5-Amino-1MQ class, because it moves from the target matters to a drug against the target does something in a live animal. And again, it is a mouse study
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It works by inhibiting the NNMT enzymea known contributor to fat storage and metabolic slowdown
Note: Individual response varies
