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PMID: 36760347 bioRxiv2023 Jan 13

B 204, 111788

- Therefore, the deficiency state is a sex-linked trait - Affected males inherit the abnormal gene from their mother, who is usually a carrier (heterozygous)

Potential Reduced Effectiveness of Birth Control There is some evidence that doxycycline may reduce the effectiveness of oral contraceptives, increasing the risk of unintended pregnancy