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A dietary cause is often managed with daily tablets, or an injection about twice a year
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Moreover, a series of studies also confirmed that 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induces mitochondrial dysfunction and ROS production, as shown by decreased MMP and ATP levels, as well as increased H 2 O 2 levels and release of cytochrome c, whereas PGC-1 overexpression partially reverses above phenomenon, thereby alleviating striatal loss of dopamine and progressive impairment of motor coordination
Lower-than-average serum BDNF is associated with cognitive impairment severity, and decreasing levels correlate with advancing Alzheimer disease