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[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Alegre-Cebollada J., Kosuri P., Giganti D., Eckels E., Rivas-Pardo J.A., Hamdani N., Warren C.M., Solaro R.J., Linke W.A., Fernndez J.M

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Under the generation of ROS and increased oxidative stress with or without inhibition of the antioxidative glutathione system of the substantia nigra, PQ elicits mitochondrial dysfunction and injury, and eventually causes neurons to embark on cell death mechanisms (Yang and Tiffany-Castiglioni, 2005

Research demonstrates that along with oxidative stress, intense activity decreases levels of glutathione, our bodys homemade antioxidant

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This, in turn, leads to hormonal imbalance and paves way for a disturbed menstrual cycle, which upon prolongation leads to oligomenorrhoea