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Data collected during the probe trials (time spent in the target quadrant and entries into the target quadrant) were also analyzed using one-way ANOVAs

One proposed mechanism involves modulation of neurotransmitter systems in the brain, particularly GABAergic, opioidergic, serotonergic, and dopaminergic pathways that are known to regulate sleep, arousal, mood, and stress responses

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We observed that in bTNF--treated bFLS, the oxidative TCA cycle is still running and could be fueled by glutamine in the culture medium via -KG