Chelation therapy for lead (treatment using agents that bind to metals in the bloodstream and help remove them from the body) is one of the few areas where a controlled trial exists
In many research models, yes
AH, SW, and JG: supervision
Two other studies also indicated that 6 months supplementation with 2 mg/d folic acid, 25 mg/d vitamin B6, and 400 mg/d B12 had favorable effects on homocysteine, disability, and severity of migraine attacks (54, 60)
Month two increases to 8-10 units daily
Mitochondrial cristae are formed by multiple folds of the inner mitochondrial membrane extending into the mitochondrial matrix (Pape et al., 2020), They include crista junctions, which connect the cristae membranes to the inner boundary membrane, and cristae tips at the distal ends of the cristae membranes (Kondadi et al., 2020)