However, it is important to note that these findings are largely limited to animal studies, and clinical evidence remains scarce
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Maccarrone and Ullrich suggested that the consideration of the redox state may be more reflective of the physiologically and pathological effects of oxidative stress than the mere absolute amounts of antioxidants and oxidants
Am J Clin Nutr 2006;83(6 suppl):1505S19S
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The IB phosphorylation and NF-B inhibitor BAY 11-7082 (also called BAY 11-7821) selectively and irreversibly inhibits TNF--induced IB phosphorylation, which lowers the expression of adhesion molecules and NF-B