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It's interesting to note that it can considerably prolong the relapse time in MS patients by lowering the levels of pro-inflammatory factor IFN- and raising the levels of anti-inflammatory factors IL-35 and IL-10 when paired with methylprednisolone (283)

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Enzymatic defects in pyruvate kinase that have been characterized include thermal lability, increased K m for PEP, and decreased activation by Fru-1,6-BP

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