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Journal Haematology 111 (2), 407415

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If you have a significant deficiency, you might start to notice an improvement in your energy and mental clarity within the first few days or after a couple of injections

What B12 does in your body Vitamin B12 (cobalamin) is a water-soluble nutrient found mainly in animal foods like meat, fish, eggs, and dairy

I can trace my symptoms back over 40 years though as you say - they did rather snow ball in the last few years

For broader pharmacokinetic context, see Peptide Half-Life Explained: Why Some Peptides Last Hours and Others Days