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It acts as a cofactor for methionine synthase and methylmalonyl-CoA mutase, enzymes that are critical for one-carbon metabolism as well as the catabolism of odd-chain fatty acids and branched-chain amino acids (Rucker et al., 2007)

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Growth hormone & IGF research: official journal of the Growth Hormone Research Society and the International IGF Research Society , 9 (2), 106113