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Pineal function and circadian biology: Studies in aged animals showing restoration of pineal gland function, increased melatonin production, and normalization of disrupted sleepwake cycles

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Clinical Benefits Supports NAD+ metabolism and mitochondrial functionkey factors in cellular energy production, vitality, and overall metabolic efficiency

Their integration offers synergistic advantages: proteomics uncovers dynamic changes in enzyme abundance, post-translational modifications and signaling pathways, wheras metabolomics captures real-time metabolic flux, substrate-product relationships, and metabolic bottlenecks ( This study aimed to elucidate the mechanisms underlying oxidative hippocampal injury in mid-late SAE using an integrated multi-omics strategy