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This observation further highlights the importance of assessing expression patterns across regions rather than disease conditions 22

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Frequently-used examples of solubility tags include GST-, MBP-, and SUMO-tags

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As such, the AMYR agonists (combined with other incretin class members) could represent the elusive drug candidate to address the multi-hormonal dysregulations of diabetes subtypes and qualify as a precision medicine approach that surpasses the long overdue division into T1DM and T2DM