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Two of the most promising new options being studied are Retatrutide and MariTide

The half-life row deserves care: both are long-acting once-weekly agents, but they get there differently CagriSema combines two separately long-acting peptides, while tirzepatide is one molecule engineered for slow clearance

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Therefore, these last poses were further computed for the intermolecular interactions between the atoms of the selected compounds and active residues in the binding pocket of the mh-Tyr protein (Table S2, Fig

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