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IGF-1 exerts its biological effect through binding to the IGF1 receptor (IGF1R), its effect is modulated through interaction with a group of binding proteins (IGFBPs), which tend to inhibit the effect of IGF-1 [2]

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212 However, clinical trials aimed at inhibiting glutathione synthesis were unsuccessful, despite some strategies having provided promising results

Because these conditions prevent adequate oral uptake, intramuscular injection bypasses the digestive system entirely and delivers B12 directly into muscle tissue for reliable absorption

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