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The study results revealed that the direct tumoral administration of the iontophoretic entity causes increased efficacy or therapeutic index due to bypassed systemic exposure of the immunotherapeutic agent as well as drastically changes the toxicity profile of the immunotherapeutic agent [207]

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To reconvert DHA into AscH , DHAR uses reduced glutathione (GSH), which is then oxidized to glutathione disulfide (GSSG)

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