Further, MTX increased the expression of PERK (Figure 6B), GRP78 (Figure 6C), ATF4 (Figure 6D), and CHOP-10 (Figure 6E) in the liver compared to CTRL, indicating that ER stress is implicated in MTX-induced hepatotoxicity
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POI: premature ovarian insufficiency
( D ) Mean relative PPP Flux in H441 cells treated with DMSO control or 1 M KEAPi (Davies et al, 2016) for 48 h and labeled with [1,2- 13 C]-glucose for 14.5 h
Appl Microbiol Biotechnol 100(21):90699080 Qiu Z, Deng Z, Tan H, Zhou S, Cao L (2015) Engineering the robustness of Saccharomyces cerevisiae by introducing bifunctional glutathione synthase gene
of Solution A + 9.7 vol