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Macrophages infected with mKate-expressing S

THF plays an important role in DNA synthesis, so reduced availability of THF results in ineffective production of cells with rapid turnover, in particular red blood cells, and also intestinal wall cells which are responsible for absorption

Beyond that, the pairing rationale is built from each compound's own data plus the CagriSema (cag + sema) Phase 3 results

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Vinogradov IV, Gamidov SI, Gabliya MY, et al

Essays Biochem 2017, 61, 177200