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However, intravenous administration of synthetic DSIP in 6 middle-aged human chronic insomniacs with disturbed sleep brought very good results, as longer sleep, higher quality with fewer interruptions and slightly more REM sleep
Such systems are usually injected in the form of sols or microspheres and can achieve rapid gelation in vivo through temperature, pH, light or ion triggering, forming a 3D support network of adhesion without damaging the surrounding tissues [60,82,83]
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Acad Radiol 19:14571464 Allen K, Jaeschke H, Copple BL (2011) Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis