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Methods: The study recruited CRAO patients from 1/2019 12/2024

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The disruption of immune tolerance leads to aberrant expression of major histocompatibility complex molecules, co-stimulatory molecules, and anti-inflammatory cytokines in the liver, thereby mediating hepatic injury ( + and CD8 + T cells while diminishing the suppressive function of Tregs, as evidenced by biopsy findings from patients experiencing immune-related hepatotoxicity ( + /CD8 + T cells play a crucial role in the digestive system-related AEs mentioned above

PMID: 24807157

Nicotinamide Adenine Dinucleotide (NAD) is a coenzyme that occurs in many living cells and functions as an electron acceptor