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Do not use phosphate-buffered saline (PBS) at high concentrations, as phosphate can compete with the peptide for copper coordination at elevated temperatures, potentially displacing the metal

That is an important framing for anyone tempted to treat it as a shortcut: even in the animal work that generates the interest, the compound is one input alongside energy balance, not a replacement for it

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Older adults are at risk of magnesium deficiency due to reduced intestinal absorption and increased urinary excretion

Neurosci ., 53 , 211213

A 93.8% encapsulation efficiency means almost none of the active ingredient is wasted before it even reaches the consumer