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and hepatic toxicity (NAFLD and cirrhosis) (Chen et al
Determination of inflammatory markers To evaluate neuroinflammation in brain tissue treated with TMX and/or LC, proinflammatory markers such as tumor necrosis factor- (TNF-), interleukin-6 (IL-6), interleukin-1 (IL-1), and nuclear factor kappa B (NF-B) were measured by enzyme-linked immunosorbent assay (ELISA) kits obtained from ABclonal and Biosourse (USA), respectively, according to the manufacturers instructions for TNF- (ABclonal, cat no
Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia
Individuals with reduced activity of the DHFR enzyme, which is responsible for the first step in folic acid metabolism, may be less able to convert folic acid efficiently
Zheng, J.v
Meanwhile, the mechanical signal-PIEZO1-ferroptosis molecular axis has been confirmed to be involved in the pathological processes of cartilage degeneration and aging (Liu et al., 2025)
