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Structurally, it increased synaptic density (synaptophysin) in females and reduced astrogliosis (GFAP) in both sexes

To accentuate all the disturbances, and to emphasize the obtained therapeutic effectiveness, we used a cuprizone regimen several times higher than those regularly used in cuprizone studies [31,155]

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Canine arthritis: Dogs develop osteoarthritis similar to humans

These findings has led to the development of NG-641, an oncolytic adenoviral vector engineered to encode four immunostimulatory transgenes, including CXCL9, CXCL10, IFN, and a bispecific T cell activator antibody targeting both FAP and CD3 [397]

Guan et al