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Repurposing of already approved drugs has been explored, for example, disulfiram, a drug traditionally used to treat alcohol dependence, can lower cystine levels in cystinotic cells, but has side effects that limit its use in cystinosis [151, 153]

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(2) investigating structureactivity relationships to identify and isolate pharmacologically active constituents

T3 level might be increased as a result of deiodinase enzyme which converts T4 into T3 [25]