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Cold fluid is more viscous and can create what some people call "thermal shock" against warm tissue

10.1258/ebm.2011.011152 Exp

Paternal physical and sedentary activities in relation to semen quality and reproductive outcomes among couples from a fertility center

Most users notice initial effects within 7-14 days, with pain reduction being the earliest indicator

Assessment of lipid peroxidation with C11-BODIPY581/591 To assess lipid peroxidation, cells were incubated with a medium containing C11-BODIPY581/591 (Dojindo, L267) for 30 min at 37 C in the dark

I made that decision mainly based on the data that I'm aware of, looking at comparison of people doing that anywhere from two to four grams of EPA per day, compared to SSRIs, selective serotonin reuptake inhibitors and treatment of depression