lingual melanotic macule Pigmented lesions of the oral mucosa and perioral tissues: a flow-chart for the diagnosis and some recommendations for the management Pigmented macule on the mandibular

Not suitable for children under 15 years of age, pregnant or breastfeeding women

This systemic view is what informs the development of next-generation research compounds, from mitochondrial protectors like SS 31 Elamipretide to metabolic modulators like Mots C Peptide

How Does CAG Work

For example, female mice exposed to EHS recovered limb skeletal muscle function and body weight within ~1 week, but if re-exposed to EHS at two weeks of recovery, they exhibited sustained atrophy and neuromuscular weakness suggesting a loss of resilience to a second stress 14

2009 Dec;60 Suppl 7:191-6

Some of these mechanisms could be investigated with the aim to potentiate the drug effects