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If response at 300mcg appears minimal after two weeks, increase to 400mcg

Patients should disclose all current medications, medical conditions, and relevant health history prior to treatment

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Hold the syringe like a pencil in your dominant hand at a 90-degree angle to the B12 injection site, and insert the needle into the skin until you feel a little pop, a sign youve reached subcutaneous tissue

The 60/40 approach places 60 percent of the dose in the morning (fasted) and 40 percent in the evening (before dinner or before bed)

[13] In a newly diagnosed vitamin B 12 -deficient patient, normally defined as when serum levels are less than 200 pg/ml, daily IM injections of hydroxocobalamin up to 1,000 g (1 mg) per day are given to replenish the body's depleted cobalamin stores