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Specifically, radiation-induced lactate accumulation in cardiomyocytes triggers P4HB lactylation at lysine 311 (K311la), which subsequently initiates inflammatory cascades and mitochondrial autophagy

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Ran J, Li F, Zhan L, Jin Y, Dong Q, Li X et al (2025) Hypoxia regulates glycolysis through the HIF-1/BMAL1/ALDOC axis to reduce oxaliplatin sensitivity in colorectal cancer

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Exercise earlier in the day generally improves sleep quality, while intense exercise close to bedtime can interfere with sleep onset for some individuals

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