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Rare risks include copper toxicity, particularly in individuals with underlying conditions such as Wilsons disease (a genetic disorder causing copper accumulation), and theoretical concerns regarding angiogenesis promotion in the context of active cancers

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This is because doxycycline is bacteriostatic (it slows bacterial growth) while penicillins are bactericidal (they kill bacteria), and these opposing mechanisms can work against each other

In this chapter, the systemic inflammation related comorbidities of psoriasis will be discussed

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