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While surgical intervention by wound debridement is the gold standard and a better therapeutic option for treating diabetic wounds, non-invasive approaches are needed

3) Common pathophysiological mechanisms involving impaired SCFA production, immune-inflammatory activation, and dysregulated neuroactive metabolite metabolism

LPa, lipoprotein(a)

In oral supplementation trials (250-1000 mg/day for up to 6 months), side effects were mild and transient, including occasional gastrointestinal symptoms

This EPO-R/CD131 selectivity allows for neuroprotection and tissue repair without the thrombotic risks of erythropoietin

These remain animal and cell-culture findings