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Gazeri A, Aminzadeh A

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Alcohol ingestion Alcohol induces liver injury and cirrhotic changes that alter drug metabolism

Mitochondrial metabolism is directly linked to 5FU sensitivity Clinically, patients with CRC usually undergo 612 cycles of 5FU-based or fluoropyrimidine-based chemotherapy 2,41

All-trans retinoic acid enhances the cytotoxic effect of decitabine on myelodysplastic syndromes and acute myeloid leukaemia by activating the RAR-Nrf2 complex

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