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In autism, a reduction in glutathione levels is observed, but also a reduced methylation capacity and lower levels of sulfate, taurine and cysteine

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J Clin Endocrinol Metab 92(4):12631268

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Although selenium is a necessary nutrient, the body has a relatively low rate of excess selenium excretion because evolutionarily selenium is a fairly uncommon nutrient to encounter

99 These discrepancies reflect methodological limitations, including species-specific auditory processing differences, variations in outcome measurements, and the challenge of modeling subjective percepts in non-human systems, thereby cautioning against direct extrapolation from animal data to human clinical contexts