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Our findings raise the question of whether ATF4-mediated ISR is generally present in these TKI-insensitive CML cells and what causes the activation of ATF4 translation in these cells

However, the normalization of those factors could probably restore normal oocyte maturation and prevent the adoption of these procedures ( Age Besides lifestyle factors, woman's age is a major factor influencing the spontaneous probability of conception that already starts to decrease by 2530 years of age

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