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Description

10.3390/ijms232214190

doi: 10.1016/j.mrfmmm.2005.08.004

SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression

somnifera, O

In mouse models of AD, specific transcriptomic patterns, referred to as microglial neurodegenerative (MGnD) or disease-associated microglia (DAM) signatures [4, 5], have been identified in subpopulations of microglia exposed to neuronal or myelin debris and associated with A plaques