The translational pathway would benefit from early thoughts from materials science, clinical, and regulatory experts to co-design delivery formats (e.g., special nanocomposite antimicrobial coatings that rapidly kill persisters on catheters) and to co-plan staged clinical trials with microbiological markers of success (i.e., MBEC reduction and no relapse) and not just surrogates of colonization
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May 2010;20(3):176-184
Circulating plasma levels of pregnenolone, progesterone, estrogen, luteinizing hormone, and follicle stimulating hormone in young and aged C57BL/6 mice during various stages of pregnancy
A BCA protein assay kit (Epizyme) was utilized for determining the protein concentration in the supernatant for subsequent calculation of the malondialdehyde (MDA) content