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BPTES-NPs treatment on mice did not elevate the plasma level of liver enzymes which CB-839 treatment did, implying a better safety profile [61]
Keywords Liver disease, Gutliver axis, Gut microbial dysbiosis, Microbial metabolites, Gut barrier, Ecological niche remodeling, Therapeutics, Multi-omics Introduction Liver diseases are one of the leading causes of death and disability worldwide, with a broad spectrum ranging from metabolic dysfunctionassociated steatotic liver disease (MASLD)/nonalcoholic fatty liver disease (NAFLD), alcoholic liver disease (ALD), and viral hepatitis to cirrhosis and hepatocellular carcinoma (HCC)
In contrast, absence seizures occur more frequently upon pharmacological inhibition of cerebellar nuclei activity [105]
It protects against amyloid-beta toxicity in vitro and dopaminergic neuronal loss in neurodegeneration models
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