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[DOI] [PubMed] [Google Scholar] 28.Su X, Dong C, Zhang J, Su L, Wang X, Cui H, et al

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Tissue Barriers 2:e944446

Patients often report enhanced mobility and a return to activities they once found challenging

According to some theories, voxelotor's ability to lessen RBC sickling enhances RBC conformation and lengthens RBC half-life, which in turn reduces whole-blood stiffness, hemolysis, and ultimately anemia [71]

Senescent cells are aged, dysfunctional cells that stop dividing but remain metabolically active, releasing inflammatory substances that harm surrounding healthy tissues