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Fatigue or feeling cold during fast weight loss Fewer cravings for alcohol, snacks, or junk food (commonly reported) When to Slow Down or Stop Vomiting that does not stop within 24 hours Severe upper abdominal pain that wraps around to the back Yellowing of skin or eyes Severe dehydration signs (dizziness, very dark urine, racing heart) Rapid weight loss over 2 lb per week sustained for many weeks (lean tissue loss risk) 13
It just has to come from the right place
The researchers observed that treatment was associated with reduced adipocyte size and altered lipid accumulation compared to control groups
This could make it harder for the body to regulate weight
The SURMOUNT-1 data showed 75% fat loss and 25% lean mass loss with tirzepatide alone
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