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While encouraging, this studys retrospective design, lack of placebo control, small sample size, and subjective outcome reporting limit its interpretability

The beneficial effects of N -acetylcysteine in ASD was supported by preclinical studies suggesting that it improved repetitive and stereotypic behaviors in autism model rats via its antioxidant properties 38

"Vitamin B12 sources and microbial interaction"

Future studies should investigate whether mitochondria-targeted interventions (e.g., exercise, NAD + precursors, mitophagy inducers) can simultaneously reduce frailty and prevent cardiometabolic-cognitive decline [40]

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