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An important open question is whether the alterations in glutamate uptake, recycling, and metabolism in neurodegenerative diseases are a consequence of disease progression or if they could be causative mechanisms driving the neurodegeneration and potentially targets for treatment [172,173]

BreuerTBleilevensCRossaintRMarxGGehrenkemperJDierksenHet al

With respect to cholesterol metabolism as it relates to NAFLD/NASH, miR-34a levels were shown to be elevated in patients with NAFLD/NASH causing a decrease in hepatic NAD-dependent deacetylase Sirtuin1 with subsequent dephosphorylation and an increase in HMGCoAr (30)

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Her approach to functional medicine and treating the root of issues was a refreshing change for me

Wu, G., Lupton, J