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Fourth, to maximize the exploration of mediators, we omitted multiple testing corrections in the two-step MR and KEGG pathway enrichment analyses, which may increase the risk of false-positive findings

doi: 10.1016/j.neuropharm.2015.08.040 Cristofori-Armstrong, Ben, Soh, Ming S., Talwar, Sahil, Brown, Darren L., Griffin, John D

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We do see a high population of these patients in our clinic