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Every fat-metabolism, NAD+, SIRT1 and lean-mass effect described above is preclinical (rodent or cell) only and should be read as a hypothesis, not an established human benefit

Mechanistic overlap: Both can influence metabolic pathways related to lipid mobilization and energy balance, though AOD-9604 is more targeted

Other populations at risk include people who had gastrointestinal surgery (including weight loss surgery) and diseases that affect the gut, such as Crohn's disease or celiac disease

however, one observational study suggests better efficacy with cyanocobalamin than with methylcobalamin

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F., Gish, W., Miller, W., Myers, E