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Carnosine is an endogenous dipeptide that functions as a buffer in muscle cells, thereby attenuating the accumulation of acidic byproducts of muscular exertion (e.g lactate and hydrogen ions) [7]

Actors in Shakespeare's day would run through the audience (often chasing other actors onto the stage), make various asides and jokes to the audience personally and usually at the expense of the other actors on stage (cf