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The review synthesized findings from cell-culture experiments (human dermal fibroblasts, keratinocytes, irradiated fibroblasts), animal models (rats, mice, pigs, dogs), and human cosmetic-science studies of topical formulations

DeRosa and Leftin, 2021)

The 10 mg group had an adjusted hazard ratio of 0.58 (95% confidence interval: 0.350.95, P = 0.03), and the 25 mg group had an adjusted hazard ratio of 0.62 (95% confidence interval: 0.380.99, P = 0.046)

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In these situations it is important to document exactly when the peptide was first added, which experimental series included it, and how it was handled relative to other reagents